Orexin A human, rat, mouse, a 33 amino acid excitatory neuropeptide, orchestrates diverse central and peripheral processes. Orexin A human, rat, mouse has been used to study its effect on the functioning of porcine pancreatic islets. It has also been used as an orexin receptor 1 (OX1R) antagonist to study the effect of orexin systems in the effect of etonogestrel on respiratory response to prolonged metabolic acidosis.

Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.

Moracin O shows significant neuroprotective, and analgesic activities, it also has a strong protective influence against doxorubicin-induced cardiomyopathy in H9c2 cells with the EC50 value of 4.5 ± 1.3 μM.